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McDonald's French Fries Cure for Hair Loss

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There has been a lot of news recently circulating the web about a new way to help you grow your hair back; eating McDonald’s French fries. This theory is based on the findings of Professor, Junji Fukada of Yokohama University in Japan. Fukada and his team of researchers have studied the form of silicone called “dimethylpolysiloxane” that is used in frying oil at McDonalds to reduce frothing.

Fukada and his team of scientists developed a method for large-scale preparation of hair follicle germs (HFGs), the reproductive source of hair follicles that grow and maintain the hair, in vitro (out of the body). They used self-organization of cells by mixing mouse epidermal (skin) cells and mouse/human mesenchymal (pluripotent connective tissue) cells and seeded them in micro-wells (single-cell cultures). Over the 3-day culture period the cells showed typical HFG features; they first formed a randomly distributed single-cell mass and then they separated from each other. These self-sorted Hair Follicle Germs, known as ssHFGs, were capable of generating shaft and hair-follicles when transplanted under the skin in the backs of nude mice. This finding paved way for the preparation of about 5,000 ssHFGs in a micro-well tool made up of oxygen-permeable silicone. This showed that the oxygen supply through the bottom was needed to enable both the formation of ssHFG and hair shaft generation.

These researchers have been successful in mass-preparing thousands of HFGs which concluded that dimethylpolysiloxane can create the vessels where HTGs could grow, but that this alone cannot stimulate hair growth.

An article in Huffington Post debunks the hair loss treatment circulating the web. Huffington Post’s article “Sorry, McDonald’s French Fries Won’t Actually Cure Your Baldness” stated that ingesting McDonald’s fries or any other of their fried foods “will have no effect whatsoever” on your hair growth.

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We have previously discussed Dr. Angela Christiano‘s work on hair loss genetics with her team at Columbia University in New York. A review of the 16th annual meeting of the European Hair Research Society; held recently in Barcelona, Spain; brings to our attention new research being conducted by a very astute scientist, Dr. Claire Higgins, who works at Dr. Christiano’s laboratory.

With tissue supplied by Bernstein Medical, Dr. Higgins is studying the inductive properties of the dermal papilla (DP), a group of cells that forms the structure directly below each hair follicle. As outlined in our Hair Cloning Methods page, the dermal papilla is of great interest to hair restoration physicians. Ideally, research of this kind will lead to a breakthrough in hair cloning or hair multiplication which will allow physicians to effectively “cure” hair loss by developing a limitless supply of donor hair that can be used in hair restoration procedures.

A description of Dr. Higgins’ work is provided by the Hair Transplant Forum International:

“After isolating [dermal papilla] from human hair follicles, they grow the human DP cells in spheroid cultures in order to retain their inductive potential. Then they place the dermal papilla spheres between the epidermis and dermis of neonatal foreskin and graft it onto the back of mice. Human [hair follicle] neogenesis can be observed after 6 weeks.”

In essence, the scientists were able to capitalize on the potential of dermal papilla cells to induce the growth of a hair follicle by enclosing the DP cells in a small sphere. When implanted, the DP cells maintained their properties of inducing the development of follicles, and, indeed, follicles did grow.

It is another example of how far our understanding of the biology of hair has come in the last 10 years. And it is another example of scientists closing in on the elusive “hair loss cure.”

Read up on the latest Hair Cloning Research

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